AChE/BChE/MAO-A-IN-2
AChE/BChE/MAO-A-IN-2 is an AChE, BChE, and MAO-A inhibitor with IC50 values of 104.28 nM, 23.04 nM, and 215.50 nM, respectively. AChE/BChE/MAO-A-IN-2 exhibits selective antiproliferative activity against cancer cells and low toxicity toward normal cells. AChE/BChE/MAO-A-IN-2 can be used for the research of alzheimer's disease, neuroblastoma.
For research use only. We do not sell to patients.
- Formula: C22H14Cl4N4O3S
- Molecular Weight:556.25
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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MAO-A 215.50 nM (IC50) |
AChE 104.28 nM (IC50) |
BChE 23.04 nM (IC50) |
AChE/BChE/MAO-A-IN-2 (compound 5n) potently and competitively inhibits purified AChE and BChE with Ki values of 92.42 and 25.35 nM, respectively[1].
AChE/BChE/MAO-A-IN-2 selectively inhibits the proliferation of SH-SY5Y human neuroblastoma cells with an IC50 of 5.23 µM, and has a selectivity index of 8.6 relative to HUVEC normal endothelial cells[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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Molecular Weight 556.25
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Formula C22H14Cl4N4O3S
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SMILES
O=C(N/N=C/C1=CN(S(=O)(C2=CC(Cl)=CC(Cl)=C2)=O)C3=C1C=CC=C3)NC4=CC=CC(Cl)=C4Cl
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
AChE/BChE/MAO-A-IN-2 Related Classifications
HY-184159 Related Classifications
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