Alamethicin F 50
Alamethicin F 50 is an antibiotic. Alamethicin F 50 is composed of membrane-active peptide, containing 75% Alamethicin F 50/5 and 10% Alamethicin F 50/7. Alamethicin F 50 is exhibits antifungal and antibacterial activity by disrupting the integrity of microbial cell membranes, resulting in leakage of cell contents and death of the microorganisms. Alamethicin F 50 is able to reduce the surface tension of water, which can be used as a surfactant or detergent.
For research use only. We do not sell to patients.
- CAS No.: 56165-93-6
- Formula: C92H151N23O24
- Molecular Weight:1963.32
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
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Biological Activity
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| MDA-MB-231 | IC50 |
5.6 μM
Compound: 1
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Cytotoxicity against human MDA-MB-231 cells assessed as decrease in cell viability after 72 hrs by CellTiter 96 AQueous one solution cell proliferation assay
Cytotoxicity against human MDA-MB-231 cells assessed as decrease in cell viability after 72 hrs by CellTiter 96 AQueous one solution cell proliferation assay
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[PMID: 28594169] |
| MDA-MB-435 | IC50 |
4.9 μM
Compound: 1
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Cytotoxicity against human MDA-MB-435 cells assessed as decrease in cell viability after 72 hrs by CellTiter 96 AQueous one solution cell proliferation assay
Cytotoxicity against human MDA-MB-435 cells assessed as decrease in cell viability after 72 hrs by CellTiter 96 AQueous one solution cell proliferation assay
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[PMID: 28594169] |
| OVCAR-3 | IC50 |
1.5 μM
Compound: 1
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Cytotoxicity against human OVCAR3 cells assessed as decrease in cell viability after 72 hrs by CellTiter 96 AQueous one solution cell proliferation assay
Cytotoxicity against human OVCAR3 cells assessed as decrease in cell viability after 72 hrs by CellTiter 96 AQueous one solution cell proliferation assay
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[PMID: 28594169] |
Chemical Information
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CAS No. 56165-93-6
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Molecular Weight 1963.32
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Formula C92H151N23O24
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Sequence
Ac-{Aib}-Pro-{Aib}-Ala-{Aib}-Ala-Gln-{Aib}-Val-{Aib}-Gly-Leu-{Aib}-Pro-Val-{Aib}-{Aib}-QQ-{L-Phenylalaninol}
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Sequence Shortening
Ac-{Aib}-P-{Aib}-A-{Aib}-AQ-{Aib}-V-{Aib}-GL-{Aib}-PV-{Aib}-{Aib}-QQ-{L-Phenylalaninol}
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Alamethicin F 50 Related Classifications
HY-P2098 Related Classifications
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