1. Antibodies
  2. Primary Antibodies
  3. PERK Antibody

PERK Antibody

Cat. No.: HY-P80781
COA User Guide for Antibodies

PERK Antibody is a non-conjugated and Rabbit origined monoclonal antibody about 125 kDa, targeting to PERK. It can be used for WB assays with tag free, in the background of Human, Mouse, Rat.

For research use only. We do not sell to patients.

Size Price Stock Quantity
Free Sample   Apply now  
10 μL $70 In-stock
50 μL $185 In-stock
100 μL $300 In-stock
250 μL   Get quote  

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Top Publications Citing Use of Products
  • Biological Activity

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Description

PERK Antibody is a non-conjugated and Rabbit origined monoclonal antibody about 125 kDa, targeting to PERK. It can be used for WB assays with tag free, in the background of Human, Mouse, Rat.

Background

PERK: The protein encoded by this gene phosphorylates the alpha subunit of eukaryotic translation-initiation factor 2, leading to its inactivation, and thus to a rapid reduction of translational initiation and repression of global protein synthesis. This protein is thought to modulate mitochondrial function. It is a type I membrane protein located in the endoplasmic reticulum (ER), where it is induced by ER stress caused by malfolded proteins. Mutations in this gene are associated with Wolcott-Rallison syndrome. [provided by RefSeq, Sep 2015]

Tag

Free

Gene ID

9451

Synonyms
EIF2AK3; PEK; PERK; Eukaryotic translation initiation factor 2-alpha kinase 3; PRKR-like endoplasmic reticulum kinase; Pancreatic eIF2-alpha kinase; HsPEK
Molecular Weight

Predicted band size: 125 kDa; Observed band size: 140 kDa

Purity

affinity purified

Conjugation

Non-conjugated

Research Field

Epigenetics and Nuclear Signaling

Product Categories

Primary Antibody; Recombinant Rabbit Monoclonal Antibody

Host

Rabbit

Reactivity

Human, Mouse, Rat

SwissProt ID

Q9NZJ5

Dilution Ratio

WB: 1:500-1:1,000

Application

WB

Appearance

Liquid

Formulation

Supplied in 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol and 0.05% BSA. Preservative: 0.01% Sodium azide

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping

Shipping with blue ice.

Isotype

IgG

Immunogen

Synthetic peptide corresponding to Human PERK.The exact sequence is proprietary to MCE.

Documentation
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
PERK Antibody
Cat. No.:
HY-P80781
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