Deltoin
Deltoin is a Coumarine derivative. Deltoin can be isolated from Seseli resinosum. Deltoin shows inhibitory activity on NO. Deltoin causes a significant inhibition against paw oedema. Deltoin shows anti-inflammatory activity.
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- CAS. Nr.: 19662-71-6
- Formel: C19H20O5
- Molecular Weight:328.36
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biologische Aktivität
Beschreibung
Cellular Effect
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| HCT-116 | IC50 |
7.6 μM
Compound: 4
|
Cytotoxicity against human HCT116 cells after 96 hrs by MTT assay
Cytotoxicity against human HCT116 cells after 96 hrs by MTT assay
|
[PMID: 23746477] |
In Vivo
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Animal Model:Sprague Dawley (male and female, 200–250 g, carrageenan-induced paw oedema model)[1]
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Dosage:5 mg/kg; 10 mg/kg; 15 mg/kg
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Administration:i.p.
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Result:Induced a 71.05% inhibition of carrageenan-induced paw oedema at 10 mg/kg; Determined an ED₅₀ value of 5.08 mg/kg.
Chemical Information
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CAS. Nr. 19662-71-6
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Molecular Weight 328.36
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Formel C19H20O5
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SMILES
C/C=C(C(OC([C@@H]1CC2=CC(C=C3)=C(C=C2O1)OC3=O)(C)C)=O)\C
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Structure Classification
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Initial Source
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)