SLC14A1 - solute carrier family 14 member 1 (Kidd blood group) Gene

Also Known as JK; UT1; UTE; HUT11; Jk(a); Jk(b); RACH1; RACH2; UT-B1; HUT11A; HsT1341

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 6563

About SLC14A1

Cytogenetic location: 18q12.3 Genomic coordinates (GRCh38): 18:45,724,181-45,752,520 (from NCBI)

This gene has 20 transcripts (splice variants), 213 orthologues, 1 paralogue and is associated with 1 phenotype. Biased expression in prostate (RPKM 18.0), urinary bladder (RPKM 11.5) and 8 other tissues.

Summary

The protein encoded by this gene is a membrane transporter that mediates urea transport in erythrocytes. This gene forms the basis for the Kidd blood group system. [provided by RefSeq, Mar 2009]

SLC14A1 Products (6)

mRNA Protein Name
NM_001128588.4 NP_001122060.3 urea transporter 1 isoform 1
NM_001146036.3 NP_001139508.2 urea transporter 1 isoform 2
NM_001146037.1 NP_001139509.1 urea transporter 1 isoform 1
NM_001308278.2 NP_001295207.1 urea transporter 1 isoform 3
NM_001308279.2 NP_001295208.1 urea transporter 1 isoform 4
NM_015865.7 NP_056949.4 urea transporter 1 isoform 2

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Verweise Source
enables protein binding IPI
IPI: Inferred from physical interaction
32296183 GOA
enables urea channel activity IDA
IDA: Inferred from direct assay
19865084 GOA
enables urea transmembrane transporter activity IDA
IDA: Inferred from direct assay
7797558 GOA
Biological Process GO Annotation Evidence Verweise Source
involved in urea transmembrane transport IDA
IDA: Inferred from direct assay
19865084 GOA
Cellular Component GO Annotation Evidence Verweise Source
located in plasma membrane IDA
IDA: Inferred from direct assay
7797558 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

SLC14A1 Protein Structure

UT

UT: Urea transporter (57 - 360)

  • 0
  • 100
  • 200
  • 300
  • 389 a.a.
Protein Preferred Names Protein Names

urea transporter 1

  • Kidd blood group antigen

Related Diseases

Diseases Alias
Blood Group, Kidd System

  • JK

  • Kidd Blood Group System

  • Blood Group, Kidd

  • Blood Group--Kidd System
Bladder Carcinoma In Situ

  • Carcinoma In Situ Of Bladder

  • Bladder Ca In Situ

  • Flat Cis Of The Urinary Bladder

  • Carcinoma In Situ Of Urinary Bladder
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Art. -Nr. Produktname
Wirkung
Reinheit
Rare Diseases
HY-RS16218 SLC14A1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS13010 SLC14A1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS27773 Slc14a1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Mus musculus SLC14A1 MGD MGI:1351654
Canis familiaris SLC14A1 VGNC VGNC:53833
Felis catus SLC14A1 VGNC VGNC:80488
Macaca mulatta SLC14A1 VGNC VGNC:104248
Rattus norvegicus SLC14A1 RGD RGD:3688
Bos taurus SLC14A1 VGNC VGNC:53653
Others SLC14A1 NCBI