L-Carnitine-13C3
Based on 1 Customer Validation
L-Carnitine-13C3 ((R)-Carnitine-13C3) is the 13C--labeled L-Carnitine (HY-B0399). L-Carnitine ((R)-Carnitine), a highly polar, small zwitterion, is an essential co-factor for the mitochondrial β-oxidation pathway. L-Carnitine functions to transport long chain fatty acyl-CoAs into the mitochondria for degradation by β-oxidation. L-Carnitine is an antioxidant. L-Carnitine can ameliorate metabolic imbalances in many inborn errors of metabolism.
Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.
- Reinheit : 98.31%
- Formel: C413C3H15NO3
- Molecular Weight:164.18
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Speicherung:
-20°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biologische Aktivität
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Chemical Information
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Lösungsmittel & Löslichkeit
- Reinheit & Dokumentation
- Verweise
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Help & FAQs
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Biologische Aktivität
Beschreibung
In Vitro
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Anwendung
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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Appearance Solid
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Molecular Weight 164.18
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Formel C413C3H15NO3
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Color White to off-white
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SMILES
[13CH3][N+]([13CH3])([13CH3])C[C@H](O)CC([O-])=O
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Synonyms
(R)-Carnitine-13C3; Levocarnitine-13C3
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
-20°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
Lösungsmittel & Löslichkeit
In Vitro:
H2O : 50 mg/mL (304.54 mM; Need ultrasonic)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
Reinheit & Dokumentation
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Data Sheet (273 KB)
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SDS (394 KB)
- English - EN (394 KB)
- Français - FR (394 KB)
- Deutsch - DE (394 KB)
- Norwegian - NO (394 KB)
- Español - ES (394 KB)
- Swedish - SV (394 KB)
- Italian - IT (394 KB)
- Korean - KR (394 KB)
- Portuguese - PT (394 KB)
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Handling Instructions (2659 KB)
Verweise
[1]. Ferreira GC, et al. L-Carnitine and Acetyl-L-carnitine Roles and Neuroprotection in Developing Brain. Neurochem Res. 2017 Jun;42(6):1661-1675. [Content Brief]
[2]. Agarwal A, et al. Role of L-carnitine in female infertility. eprod Biol Endocrinol. 2018 Jan 26;16(1):5. [Content Brief]
[3]. Ferreira GC, et al. L-Carnitine and Acetyl-L-carnitine Roles and Neuroprotection in Developing Brain. Neurochem Res. 2017;42(6):1661-1675. [Content Brief]
[4]. Uzuner N, et al. The role of L-carnitine in treatment of a murine model of asthma. Acta Med Okayama. 2002 Dec;56(6):295-301. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| H2O | 1 mM | 6.0909 mL | 30.4544 mL | 60.9088 mL | 152.2719 mL |
| 5 mM | 1.2182 mL | 6.0909 mL | 12.1818 mL | 30.4544 mL | |
| 10 mM | 0.6091 mL | 3.0454 mL | 6.0909 mL | 15.2272 mL | |
| 15 mM | 0.4061 mL | 2.0303 mL | 4.0606 mL | 10.1515 mL | |
| 20 mM | 0.3045 mL | 1.5227 mL | 3.0454 mL | 7.6136 mL | |
| 25 mM | 0.2436 mL | 1.2182 mL | 2.4364 mL | 6.0909 mL | |
| 30 mM | 0.2030 mL | 1.0151 mL | 2.0303 mL | 5.0757 mL | |
| 40 mM | 0.1523 mL | 0.7614 mL | 1.5227 mL | 3.8068 mL | |
| 50 mM | 0.1218 mL | 0.6091 mL | 1.2182 mL | 3.0454 mL | |
| 60 mM | 0.1015 mL | 0.5076 mL | 1.0151 mL | 2.5379 mL | |
| 80 mM | 0.0761 mL | 0.3807 mL | 0.7614 mL | 1.9034 mL | |
| 100 mM | 0.0609 mL | 0.3045 mL | 0.6091 mL | 1.5227 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
L-Carnitine-13C3 Related Classifications
HY-B0399S2 Related Classifications
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