2. MAPK/ERK Pathway
  3. Raf
  4. B-Raf IN 8

B-Raf IN 8 (compound 7g) is a potent B-Raf inhibitor, with an IC50 of 70.65 nM. B-Raf IN 8 exhibits antitumor activity against hepatocellular carcinoma (HEPG-2), colon carcinoma (HCT-116), mammary gland (MCF-7) and human prostate cancer (PC-3) cells, with IC50 values of 9.78, 13.78, 18.52 and 29.85 µM.

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B-Raf IN 8

B-Raf IN 8 화학구조

CAS No. : 1215313-19-1

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B-Raf IN 8 Related Antibodies

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제품 설명

B-Raf IN 8 (compound 7g) is a potent B-Raf inhibitor, with an IC50 of 70.65 nM. B-Raf IN 8 exhibits antitumor activity against hepatocellular carcinoma (HEPG-2), colon carcinoma (HCT-116), mammary gland (MCF-7) and human prostate cancer (PC-3) cells, with IC50 values of 9.78, 13.78, 18.52 and 29.85 µM[1].

IC50 & Target

B-Raf

70.65 ± 0. nM (IC50)

분자량

307.35

화학식

C18H17N3O2
CAS No.
SMILES

O=C1CCC(C2=CC=C(/N=C/C3=CC=C(OC)C=C3)C=C2)=NN1
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
References
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B-Raf IN 8 Related Classifications

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Keywords:

B-Raf IN 81215313-19-1RafRaf kinasesHCT-116PC-3 cellHEPG2MCF-7antitumorB-Rafcell cyclepyridazinoneprostate cancerInhibitorinhibitorinhibit

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B-Raf IN 8
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