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A253 cell line

Definition:

A253 cell line is a human cancer cell line derived from Salivary gland, submandibular gland and associated with Submandibular gland squamous cell carcinoma and Malignant epithelial tumor of salivary glands. Its continuous tumor-cell growth supports reproducible mechanistic and pharmacological experiments. A253 cell line is used as an in vitro model of Submandibular gland squamous cell carcinoma and Malignant epithelial tumor of salivary glands to investigate tumor-cell growth, cell survival, and pharmacological response.

References:

[1]. Wustrow TP, Raffael A, Valet G. Multiparametric flow cytometry of human squamous cell carcinoma lines from the head and neck. Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery. 1988;98(6):552-7.

[2]. Lin LC, et al. Cross-contamination of the human salivary gland HSG cell line with HeLa cells: A STR analysis study. Oral diseases. 2018;24(8):1477-1483.

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