Caveolae-associated protein 2

Definition:

Plays an important role in caveolar biogenesis and morphology. Regulates caveolae morphology by inducing membrane curvature within caveolae. Plays a role in caveola formation in a tissue-specific manner. Required for the formation of caveolae in the lung and fat endothelia but not in the heart endothelia. Negatively regulates the size or stability of CAVIN complexes in the lung endothelial cells. May play a role in targeting PRKCA to caveolae (By similarity).

References:

[1]. Carsten G Hansen, et al. SDPR induces membrane curvature and functions in the formation of caveolae. Nat Cell Biol. 2009 Jul;11(7):807-14. [Content Brief]

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