Centriolin

Definition:

Involved in cell cycle progression and cytokinesis. During the late steps of cytokinesis, anchors exocyst and SNARE complexes at the midbody, thereby allowing secretory vesicle-mediated abscission.

References:

[1]. Adam Gromley, et al. Centriolin anchoring of exocyst and SNARE complexes at the midbody is required for secretory-vesicle-mediated abscission. Cell. 2005 Oct 7;123(1):75-87. [Content Brief]

[2]. Adam Gromley, et al. A novel human protein of the maternal centriole is required for the final stages of cytokinesis and entry into S phase. J Cell Biol. 2003 May 12;161(3):535-45. [Content Brief]

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