Protein phosphatase 1D
Definition:
References:
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[1]. Xiongbin Lu, et al. PPM1D dephosphorylates Chk1 and p53 and abrogates cell cycle checkpoints. Genes Dev. 2005 May 15;19(10):1162-74. [Content Brief]
[2]. H Fujimoto, et al. Regulation of the antioncogenic Chk2 kinase by the oncogenic Wip1 phosphatase. Cell Death Differ. 2006 Jul;13(7):1170-80. [Content Brief]
[3]. Elise Ruark, et al. Mosaic PPM1D mutations are associated with predisposition to breast and ovarian cancer. Nature. 2013 Jan 17;493(7432):406-10. [Content Brief]
[4]. Hanbing An, et al. LZAP inhibits p38 MAPK (p38) phosphorylation and activity by facilitating p38 association with the wild-type p53 induced phosphatase 1 (WIP1). PLoS One. 2011 Jan 24;6(1):e16427. [Content Brief]