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SK-MM-2

Definition:

SK-MM-2 is a human Plasma cell-derived cancer cell line derived from Peripheral blood and associated with Plasma cell myeloma and Multiple myeloma. Its continuous tumor-cell growth supports reproducible mechanistic and pharmacological experiments. SK-MM-2 is used as an in vitro model of Plasma cell myeloma and Multiple myeloma to investigate tumor-cell growth, cell survival, and pharmacological response.

References:

[1]. Eton O, Scheinberg DA, Houghton AN. Establishment and characterization of two human myeloma cell lines secreting kappa light chains. Leukemia. 1989;3(10):729-35.

[2]. Drexler HG, Matsuo Y. Malignant hematopoietic cell lines: in vitro models for the study of multiple myeloma and plasma cell leukemia. Leukemia research. 2000;24(8):681-703.

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