Sugar phosphate backbone

Definition:

Sugar phosphate backbone forms the structural framework of nucleic acids, including DNA and RNA. This backbone is composed of alternating sugar and phosphate groups, and defines directionality of the molecule.

References:

[1]. Šponer J, et al. The DNA and RNA sugar-phosphate backbone emerges as the key player. An overview of quantum-chemical, structural biology and simulation studies. Phys Chem Chem Phys. 2012 Nov 28;14(44):15257-77. [Content Brief]

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