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SW620/AD300

Definition:

SW620/AD300 is a human cancer cell line derived from Lymph node and associated with Colon adenocarcinoma. SW620/AD300 is a resistant derivative of SW620 selected against Adriamycin. SW620/AD300 is used as an in vitro model of Colon adenocarcinoma to investigate membrane transport.

References:

[1]. Gao HL, et al. The AKT inhibitor, MK-2206, attenuates ABCG2-mediated drug resistance in lung and colon cancer cells. Frontiers in pharmacology. 2023;14:1235285.

[2]. Cui Q, et al. Glesatinib, a c-MET/SMO Dual Inhibitor, Antagonizes P-glycoprotein Mediated Multidrug Resistance in Cancer Cells. Frontiers in oncology. 2019;9:313. [Content Brief]

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