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SW872

Definition:

SW872 is a human cancer cell line and associated with Liposarcoma. Its continuous tumor-cell growth supports reproducible mechanistic and pharmacological experiments. SW872 is used as an in vitro model of Liposarcoma to investigate apoptosis, inflammatory signaling, mitochondrial function, and receptor signaling and trafficking.

References:

[1]. Briones-Suarez L, Cifuentes M, Bravo-Sagua R. Secretory Factors from Calcium-Sensing Receptor-Activated SW872 Pre-Adipocytes Induce Cellular Senescence and A Mitochondrial Fragmentation-Mediated Inflammatory Response in HepG2 Cells. International journal of molecular sciences. 2023;24(6).

[2]. Samsuzzaman M, Jang BC. Growth-Suppressive and Apoptosis-Inducing Effects of Tetrandrine in SW872 Human Malignant Liposarcoma Cells via Activation of Caspase-9, Down-Regulation of XIAP and STAT-3, and ER Stress. Biomolecules. 2022;12(6).

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