Syphilis

Definition:

Syphilis is one of the oldest recognized venereal infections caused by the spirochete Treponema pallidum subsp. pallidum. It is characterized by genital ulceration, skin rash, and development of serious systemic disease. Syphilis may also alter the course of HIV disease. Effective therapy is available but the incidence is increasing in many parts of the world.

References:

[1]. Demetre Daskalakis, et al. Syphilis: continuing public health and diagnostic challenges. Curr HIV/AIDS Rep. 2008 May;5(2):72-7. [Content Brief]

[2]. Emily L Ho, et al. Syphilis: using modern approaches to understand an old disease. J Clin Invest. 2011 Dec;121(12):4584-92. [Content Brief]

[3]. Georg Michael Antal, et al. The endemic treponematoses. Microbes Infect. 2002 Jan;4(1):83-94. [Content Brief]

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