Boc-Asp(OMe)-fluoromethyl ketone (Standard)
Boc-Asp(OMe)-fluoromethyl ketone (Standard) is the analytical standard of Boc-Asp(OMe)-fluoromethyl ketone (HY-103348). This product is intended for research and analytical applications. Boc-Asp(OME)-Fluoromethyl Ketone is a broad range caspase inhibitor that inhibits Fas-mediated phagocytosis and oxidative rupture inhibition, but does not affect the chemotactic activity of IL-8.
For research use only. We do not sell to patients.
- CAS No.: 187389-53-3
- Formula: C11H18FNO5
- Molecular Weight:263.26
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Product Information
Information
Application
The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.
Chemical Information
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CAS No. 187389-53-3
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Molecular Weight 263.26
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Formula C11H18FNO5
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SMILES
O=C(OC)C[C@H](NC(OC(C)(C)C)=O)C(CF)=O
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Synonyms
Boc-Asp(OMe)-FMK (Standard)
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Paunel-Görgülü A, et al. Stimulation of Fas signaling down-regulates activity of neutrophils from major trauma patients with SIRS. Immunobiology. 2011;216(3):334-342. [Content Brief]
[2]. Koike A, et al. Pan-caspase inhibitors induce necroptosis via ROS-mediated activation of mixed lineage kinase domain-like protein and p38 in classically activated macrophages. Exp Cell Res. 2019;380(2):171-179. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)