1. Signaling Pathways
  2. Apoptosis
  3. Caspase
  4. Caspase Isoform
  5. Caspase Inhibitor

Caspase Inhibitor

Caspase Inhibitors (27):

Cat. No. Product Name Effect Purity
  • HY-16658B
    Z-VAD-FMK
    Inhibitor 99.76%
    Z-VAD-FMK (Z-VAD(OH)-FMK) is a well-know pan caspase inhibitor, which does not inhibit ubiquitin carboxy-terminal hydrolase L1 (UCHL1) activity even at concentrations as high as 440 μM.
  • HY-16658
    Z-VAD(OMe)-FMK
    Inhibitor 98.20%
    Z-VAD(OMe)-FMK (Z-Val-Ala-Asp(OMe)-FMK) is a cell-permeable and irreversible pan-caspase inhibitor.
  • HY-10396
    Emricasan
    Inhibitor 99.59%
    Emricasan (PF 03491390) is an orally active and irreversible pan-caspase inhibitor.
  • HY-P1009
    Z-YVAD-FMK
    Inhibitor ≥98.0%
    Z-YVAD-FMK is a cell-permeable caspase-1 and -4 inhibitor with anti-inflammatory and anti-tumor activities.
  • HY-13229
    BOC-D-FMK
    Inhibitor
    Boc-D-FMK is a cell-permeable, irreversible and broad spectrum caspase inhibitor.
  • HY-18705
    Azoramide
    Inhibitor 98.63%
    Azoramide is a potent, orally active small-molecule modulator of the unfolded protein response (UPR).
  • HY-N0745
    Senkyunolide I
    Inhibitor 98.54%
    Senkyunolide I, isolated from Ligusticum chuanxiong Hort, is an anti-migraine compound.
  • HY-N0809
    Sesamolin
    Inhibitor 99.78%
    Sesaminol, isolated from Sesamum indicum, has antioxidative activity, Sesaminol inhibits lipid peroxidation and shows neuroprotection effect.
  • HY-N6777
    Penicillic acid
    Inhibitor 99.83%
    Penicillic acid is a polyketide mycotoxin produced by several species of Aspergillus and Penicillium.
  • HY-100472
    ZYZ-488
    Inhibitor 99.80%
    ZYZ-488 is a competitive apoptotic protease activating factor-1 (Apaf-1) inhibitor.
  • HY-N2013
    Aristolactam I
    Inhibitor 99.69%
    Aristololactam I (AL-I), is the main metabolite of aristolochic acid I (AA-I), participates in the processes that lead to renal damage.
  • HY-113953
    Z-Asp-CH2-DCB
    Inhibitor 99.28%
    Z-Asp-CH2-DCB is an irreversible broad spectrum caspase inhibitor.
  • HY-141622
    SDZ 224-015
    Inhibitor
    SDZ 224-015 is an orally active inhibitor of the interleukin-1 beta (IL-1β) converting enzyme and caspase-1.
  • HY-10397
    EP1013
    Inhibitor
    EP1013 (F1013) is a broad-spectrum caspase selective inhibitor, used in the research of type 1 diabetes.
  • HY-100894
    Biotin-VAD-FMK
    Inhibitor ≥98.0%
    Biotin-VAD-FMK is a cell permeable, irreversible biotin-labeled caspase inhibitor, used to identify active caspases in cell lysates.
  • HY-125018
    QM31
    Inhibitor 98.50%
    QM31 (SVT016426), a cytoprotective agent, is a selective inhibitor of Apaf-1.
  • HY-148258
    GDC-2394
    Inhibitor
    GDC-2394 is an orally active and selective NLRP3 inhibitor, and also inhibits IL-1β with IC50s of 0.4 μM (human IL-1β) and 0.1 μM (mouse IL-1β).
  • HY-10397A
    MX1013
    Inhibitor ≥99.0%
    MX1013 is a potent, irreversible dipeptide caspase inhibitor vith antiapoptotic activity.
  • HY-103348
    Boc-Asp(OMe)-fluoromethyl ketone
    Inhibitor
    Boc-Asp(OME)-Fluoromethyl Ketone is a broad range caspase inhibitor that inhibits Fas-mediated phagocytosis and oxidative rupture inhibition, but does not affect the chemotactic activity of IL-8.
  • HY-138203
    Z-LE(OMe)TD(OMe)-FMK
    Inhibitor
    Z-LE(OMe)TD(OMe)-FMK is a selective caspase-8 inhibitor.