352520-90-2
352520-90-2
Chemical Structure
Ac-IEPD-CHO
- CAS No.: 352520-90-2
- Formula:C22H34N4O9
- Molecular Weight:498.53
InChIKey: JFFGRTYAQZRQMF-RWBKLUSOSA-N
SMILES: CC[C@H](C)[C@H](NC(C)=O)C(N[C@@H](CCC(O)=O)C(N1[C@@H](CCC1)C(N[C@H](C=O)CC(O)=O)=O)=O)=O
Biological Activity: Ac-IEPD-CHO is a reversible granzyme B inhibitor with a Ki of 80 nM[1]. Ac-IEPD-CHO is also a caspase-8 inhibitor[2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Ac-IEPD-CHO | 99.91% | Ac-IEPD-CHO is a reversible granzyme B inhibitor with a Ki of 80 nM. Ac-IEPD-CHO is also a caspase-8 inhibitor. | ||||||||||||||||||||
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References
- [1]. Mi-Sun Kim, et al. Approaches to design non-covalent inhibitors for human granzyme B (hGrB). Org Biomol Chem. 2014 Nov 28;12(44):8952-65. [Content Brief]
- [2]. In-Sun Hong, et al. Gonadotropin-releasing hormones I and II induce apoptosis in human granulosa cells. J Clin Endocrinol Metab. 2008 Aug;93(8):3179-85. [Content Brief]
Keywords
