1. Apoptosis
  2. Caspase
  3. Ivachtin

Ivachtin (Synonyms: Caspase-3 Inhibitor VII)

Cat. No.: HY-P1095 Purity: >99.0%
Handling Instructions

Ivachtin (Caspase-3 Inhibitor VII; compound 7a) is a nonpeptide, noncompetitive and reversibl caspase-3 inhibitor with an IC50 of 23 nM. Ivachtin has modest selectivity for the remaining caspases.

For research use only. We do not sell to patients.

Ivachtin Chemical Structure

Ivachtin Chemical Structure

CAS No. : 745046-84-8

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Description

Ivachtin (Caspase-3 Inhibitor VII; compound 7a) is a nonpeptide, noncompetitive and reversibl caspase-3 inhibitor with an IC50 of 23 nM. Ivachtin has modest selectivity for the remaining caspases[1].

IC50 & Target[1]

Caspase-3

23 nM (IC50)

In Vitro

Ivachtin (Caspase-3 Inhibitor VII; compound 7a; 10, 100 μM) has protective effect in a model of staurosporininduced apoptosis in human Jurkat T cells[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

447.46

Formula

C₂₀H₂₁N₃O₇S

CAS No.

745046-84-8

SMILES

O=C1N(CCOC(C)=O)C(C2=C1C3=CC(S(=O)(N4CCOCC4)=O)=CC=C3N=C2C)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -80°C 2 years
-20°C 1 year
In solvent -80°C 6 months
-20°C 1 month
References
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Keywords:

IvachtinCaspase-3 Inhibitor VIICaspasenonpeptidenoncompetitivereversiblmodestselectivitycaspasesstaurosporininducedapoptosisInhibitorinhibitorinhibit

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