1. Apoptosis
  2. Caspase
  3. Ivachtin

Ivachtin  (Synonyms: Caspase-3 Inhibitor VII)

Cat. No.: HY-P1095 Purity: ≥98.0%
COA Handling Instructions

Ivachtin (Caspase-3 Inhibitor VII; compound 7a) is a nonpeptide, noncompetitive and reversibl caspase-3 inhibitor with an IC50 of 23 nM. Ivachtin has modest selectivity for the remaining caspases.

For research use only. We do not sell to patients.

Ivachtin Chemical Structure

Ivachtin Chemical Structure

CAS No. : 745046-84-8

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Based on 1 publication(s) in Google Scholar

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Description

Ivachtin (Caspase-3 Inhibitor VII; compound 7a) is a nonpeptide, noncompetitive and reversibl caspase-3 inhibitor with an IC50 of 23 nM. Ivachtin has modest selectivity for the remaining caspases[1].

IC50 & Target[1]

Caspase-3

23 nM (IC50)

In Vitro

Ivachtin (Caspase-3 Inhibitor VII; compound 7a; 10, 100 μM) has protective effect in a model of staurosporininduced apoptosis in human Jurkat T cells[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

447.46

Formula

C20H21N3O7S

CAS No.
Appearance

Solid

Color

White to yellow

SMILES

O=C1N(CCOC(C)=O)C(C2=C1C3=CC(S(=O)(N4CCOCC4)=O)=CC=C3N=C2C)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Purity & Documentation

Purity: ≥99.0%

References
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Ivachtin Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Ivachtin
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