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Cat. No.: HY-105500

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BW-1003C87 Ethylsulfate

BW-1003C87 Ethylsulfate is a glutamate release inhibitor. BW-1003C87 Ethylsulfate exhibit neuroprotective effect. BW-1003C87 Ethylsulfate can elevate seizure threshold. BW-1003C87 Ethylsulfate can be used for the research of neurological disease, such as ischemic and seizure.

For research use only. We do not sell to patients.

CAS No.: 144425-86-5
Formula: C₁₂H₁₃Cl₃N₄O₃S
Molecular Weight:399.68

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (274 KB)

BW-1003C87 Ethylsulfate Chemical Structure

CAS No.: 144425-86-5

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Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
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- In Vivo
Chemical Information
Purity & Documentation
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Biological Activity

Description

All Sodium Channel Isoforms :

In Vivo

BW-1003C87 Ethylsulfate (10 mg/kg, i.p.) reduces the brain damage by 46% in rat pups subjected to hypoxia-ischemia^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 144425-86-5
Molecular Weight 399.68
Formula C₁₂H₁₃Cl₃N₄O₃S
SMILES

CCS(=O)(O)=O.NC1=NC(N)=NC=C1C2=C(C(Cl)=CC(Cl)=C2)Cl
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (274 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Gilland E, et al. Hypoxic-ischemic injury in the neonatal rat brain: effects of pre- and post-treatment with the glutamate release inhibitor BW1003C87. Brain Res Dev Brain Res. 1994 Nov 18;83(1):79-84. [Content Brief]

[2]. Morimoto K, et al. BW1003C87, phenytoin and carbamazepine elevate seizure threshold in the rat amygdala-kindling model of epilepsy. Eur J Pharmacol. 1997 Nov 19;339(1):11-5. [Content Brief]

[3]. Gaspary HL, et al. BW1003C87 and NBQX but not CGS19755 reduce glutamate release and cerebral ischemic necrosis. Eur J Pharmacol. 1994 Sep 12;262(3):197-203. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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Biological Activity
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BW-1003C87 Ethylsulfate

All Sodium Channel Isoforms

Biological Activity

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

BW-1003C87 Ethylsulfate Related Classifications

HY-105500 Related Classifications