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Cat. No.: HY-105500

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BW-1003C87 Ethylsulfate

BW-1003C87 Ethylsulfate is a glutamate release inhibitor. BW-1003C87 Ethylsulfate exhibit neuroprotective effect. BW-1003C87 Ethylsulfate can elevate seizure threshold. BW-1003C87 Ethylsulfate can be used for the research of neurological disease, such as ischemic and seizure.

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CAS No.: 144425-86-5
Formule: C₁₂H₁₃Cl₃N₄O₃S
Masse moléculaire:399.68

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Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (274 KB)

BW-1003C87 Ethylsulfate Chemical Structure

CAS No.: 144425-86-5

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Description

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In Vivo

BW-1003C87 Ethylsulfate (10 mg/kg, i.p.) reduces the brain damage by 46% in rat pups subjected to hypoxia-ischemia^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 144425-86-5
Masse moléculaire 399.68
Formule C₁₂H₁₃Cl₃N₄O₃S
SMILES

CCS(=O)(O)=O.NC1=NC(N)=NC=C1C2=C(C(Cl)=CC(Cl)=C2)Cl
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

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Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

Fiche technique (274 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instruction de manipulation (2659 KB)

Références

[1]. Gilland E, et al. Hypoxic-ischemic injury in the neonatal rat brain: effects of pre- and post-treatment with the glutamate release inhibitor BW1003C87. Brain Res Dev Brain Res. 1994 Nov 18;83(1):79-84. [Content Brief]

[2]. Morimoto K, et al. BW1003C87, phenytoin and carbamazepine elevate seizure threshold in the rat amygdala-kindling model of epilepsy. Eur J Pharmacol. 1997 Nov 19;339(1):11-5. [Content Brief]

[3]. Gaspary HL, et al. BW1003C87 and NBQX but not CGS19755 reduce glutamate release and cerebral ischemic necrosis. Eur J Pharmacol. 1994 Sep 12;262(3):197-203. [Content Brief]

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BW-1003C87 Ethylsulfate

Voir tous les produits spécifiques à Isoform Sodium Channel

Activité biologique

Chemical Information

Pureté et documentation

Références

Calculators

Help & FAQs

BW-1003C87 Ethylsulfate Related Classifications

HY-105500 Related Classifications