CUHK242
CUHK242 is a bacterial transcription inhibitor, with a MIC of 2 μg/mL for B. subtilis reporter strain BS2019. CUHK242 has antimicrobial activity against Staphylococcus aureus. CUHK242 can inhibit RNA synthesis in cells, thereby simultaneously reducing protein synthesis.
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- CAS No.: 2408055-05-8
- Formule: C20H13Cl3N2O4S
- Masse moléculaire:483.75
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Activité biologique
Description
Cellular Effect
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| A549 | CC50 |
75.7 μM
Compound: 54
|
Cytotoxicity against human A549 cells after 48 to 72 hrs by MTT assay
Cytotoxicity against human A549 cells after 48 to 72 hrs by MTT assay
|
[PMID: 32633513] |
| HepG2 | CC50 |
74.4 μM
Compound: 54
|
Cytotoxicity against human HepG2 cells after 48 to 72 hrs by MTT assay
Cytotoxicity against human HepG2 cells after 48 to 72 hrs by MTT assay
|
[PMID: 32633513] |
Chemical Information
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CAS No. 2408055-05-8
-
Masse moléculaire 483.75
-
Formule C20H13Cl3N2O4S
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SMILES
O=C(O)C1=CC=C(Cl)C=C1NCC2=CC=C(SC3=CC=C(Cl)C(Cl)=C3)C([N+]([O-])=O)=C2
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Livraison
Room temperature in continental US; may vary elsewhere.
-
Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)