Mapre1 - microtubule-associated protein, RP/EB family, member 1 Gene

Also Known as Eb1; BIM1p; D2Ertd459e; 5530600P05Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 13589

Summary

Enables microtubule plus-end binding activity. Involved in microtubule bundle formation and microtubule polymerization. Acts upstream of or within non-motile cilium assembly; positive regulation of microtubule plus-end binding activity; and protein localization to microtubule Cytoskeleton. Located in Golgi apparatus; cell projection membrane; and microtubule Cytoskeleton. Is expressed in several structures, including alimentary system; brain; genitourinary system; hemolymphoid system gland; and liver and biliary system. Orthologous to human MAPRE1 (microtubule associated protein RP/EB family member 1). [provided by Alliance of Genome Resources, Apr 2022]

Mapre1 Products (1)

mRNA Protein Name
NM_007896.3 NP_031922.1 microtubule-associated protein RP/EB family member 1

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Références Source
enables microtubule plus-end binding IDA
IDA: Inferred from direct assay
16148041 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
16148041 MGI
Biological Process GO Annotation Evidence Références Source
involved in microtubule bundle formation IDA
IDA: Inferred from direct assay
24706950 MGI
involved in microtubule polymerization IDA
IDA: Inferred from direct assay
24706950 MGI
acts upstream of or within non-motile cilium assembly IMP
IMP: Inferred from mutant phenotype
17600711 MGI
acts upstream of or within positive regulation of microtubule plus-end binding IDA
IDA: Inferred from direct assay
16148041 MGI
acts upstream of or within positive regulation of microtubule plus-end binding IGI
IGI: Inferred from genetic interaction
16148041 MGI
acts upstream of or within protein localization to centrosome IMP
IMP: Inferred from mutant phenotype
17600711 MGI
acts upstream of or within protein localization to microtubule IMP
IMP: Inferred from mutant phenotype
16247022 MGI
Cellular Component GO Annotation Evidence Références Source
located in Golgi apparatus IDA
IDA: Inferred from direct assay
11290329 MGI
located in cell projection IDA
IDA: Inferred from direct assay
16525027 MGI
located in cell projection membrane IDA
IDA: Inferred from direct assay
16621792 MGI
located in ciliary basal body IDA
IDA: Inferred from direct assay
17600711 MGI
located in microtubule IDA
IDA: Inferred from direct assay
18854161 MGI
located in microtubule cytoskeleton IDA
IDA: Inferred from direct assay
11290329 MGI
located in microtubule plus-end IDA
IDA: Inferred from direct assay
17600711 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

microtubule-associated protein RP/EB family member 1

  • APC-binding protein EB1

  • adenomatosis polyposis coli binding protein Eb1

  • end-binding protein 1

Mapre1 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method Références
Cross
Mapre1 Q61166 DST Homo sapiens Q03001
Pull Down
22995871
Cross
Mapre1 Q61166 DST Homo sapiens Q03001
Anti Tag CoIP
26496610
Intra
Mapre1 Q61166 Map1b Mus musculus P14873
Anti Bait CoIP
23572079
Intra
Mapre1 Q61166 Map1b Mus musculus P14873
Confocal
23572079
Intra
Mapre1 Q61166 Map1b Mus musculus P14873
Pull Down
23572079
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Nom du produit
Effect
Pureté
Rare Diseases
HY-RS08137 MAPRE1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS21152 Mapre1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS27668 Mapre1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Mapre1 NCBI NCBI:22919