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Cat. No.: HY-161283

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JT21-25

JT21-25 (compound 9h) is a potent and selective inhibitor of apoptosis signal-regulating kinase 1 (ASK1), with IC₅₀ of 5.1 nM.

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CAS No.: 2996864-57-2
Formule: C₂₀H₁₇BrN₆O
Masse moléculaire:437.29

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Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (268 KB)

JT21-25 Chemical Structure

CAS No.: 2996864-57-2

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Activité biologique
- Description
- IC₅₀ & Target
Chemical Information
Pureté et documentation
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Calculators
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Activité biologique

Description

JT21-25 (compound 9h) is a potent and selective inhibitor of apoptosis signal-regulating kinase 1 (ASK1), with IC₅₀ of 5.1 nM^[1].

IC₅₀ & Target

ASK1

5.1 nM (IC₅₀)

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Chemical Information

CAS No. 2996864-57-2
Masse moléculaire 437.29
Formule C₂₀H₁₇BrN₆O
SMILES

BrC1=CC=CC2=C1N=C(C(NC3=NC(C4=NN=CN4C(C)C)=CC=C3)=O)C=C2
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

Select Batch:

Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

Fiche technique (268 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instruction de manipulation (2659 KB)

Références

[1]. Lidan Pang, et al. Discovery of a quinoline-containing compound JT21-25 as a potent and selective inhibitor of apoptosis signal-regulating kinase 1 (ASK1). Bioorg Chem. 2024 Mar:144:107167. [Content Brief]

Calculators

Calculateur de molarité

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

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100 mg

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- IC₅₀ & Target
Chemical Information
Pureté et documentation
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JT21-25

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Activité biologique

Description

IC50 & Target

Chemical Information

Pureté et documentation

Références

Calculators

Help & FAQs

JT21-25 Related Classifications

HY-161283 Related Classifications

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