MNA 279
MNA 279 (X 910279) is an orally active, immunosuppressive malononitrilamide and A 771726 derivative. MNA 279 suppresses IgM and IgG antibody production. MNA 279 prevents the development of systemic lupus erythematosus (SLE)-like disease in mice. MNA 279 prolongs skin xenograft survival in a mouse-to-rat model.
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- CAS No.: 185915-32-6
- Formule: C14H11N3O2
- Masse moléculaire:253.26
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Activité biologique
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Chemical Information
- Pureté et documentation
- Références
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Help & FAQs
Activité biologique
Chemical Information
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CAS No. 185915-32-6
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Masse moléculaire 253.26
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Formule C14H11N3O2
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SMILES
N#CC1=CC=C(NC(C(C(C2CC2)=O)C#N)=O)C=C1
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Synonyms
X 910279; HMR-279; FK-779
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
[1]. Schorlemmer HU, et al. Prevention of the development of murine systemic lupus erythematosus (SLE)-like diseases by the malononitrilamides MNA 279 and MNA 715. Inflamm Res. 1997 Aug;46 Suppl 2:S167-8. [Content Brief]
[2]. Schorlemmer HU, et al. The new immunosuppressive malononitrilamide MNA 279 prolongs skin xenograft survival in a mouse-to-rat model. Transplant Proc. 1997 Dec;29(8):3497-500. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
MNA 279 Related Classifications
HY-129442 Related Classifications
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