(S)-NIK SMI1
Based on 1 Customer Validation
(S)-NIK SMI1 is the isomer of NIK SMI1 (HY-112433), and can be used as an experimental control. NIK SMI1 is a potent, selective NF-κB inducing kinase (NIK) inhibitor, which inhibits NIK-catalyzed hydrolysis of ATP to ADP with IC50 of 0.23±0.17 nM.
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- Pureté : 99.28%
- CAS No.: 2984765-48-0
- Formule: C20H19N3O4
- Masse moléculaire:365.38
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Stockage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
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Activité biologique
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Chemical Information
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Solvant et solubilité
- Pureté et documentation
- Références
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Help & FAQs
Activité biologique
Description
Chemical Information
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CAS No. 2984765-48-0
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Appearance Solid
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Masse moléculaire 365.38
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Formule C20H19N3O4
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Color Off-white to pink
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SMILES
O=C(N)C1=NC(C2=CC=CC(C#C[C@@]3(O)CCN(C)C3=O)=C2)=CC(OC)=C1
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvant et solubilité
In Vitro:
DMSO : 100 mg/mL (273.69 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Pureté et documentation
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Fiche technique (273 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Instruction de manipulation (2659 KB)
Références
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.7369 mL | 13.6844 mL | 27.3688 mL | 68.4219 mL |
| 5 mM | 0.5474 mL | 2.7369 mL | 5.4738 mL | 13.6844 mL | |
| 10 mM | 0.2737 mL | 1.3684 mL | 2.7369 mL | 6.8422 mL | |
| 15 mM | 0.1825 mL | 0.9123 mL | 1.8246 mL | 4.5615 mL | |
| 20 mM | 0.1368 mL | 0.6842 mL | 1.3684 mL | 3.4211 mL | |
| 25 mM | 0.1095 mL | 0.5474 mL | 1.0948 mL | 2.7369 mL | |
| 30 mM | 0.0912 mL | 0.4561 mL | 0.9123 mL | 2.2807 mL | |
| 40 mM | 0.0684 mL | 0.3421 mL | 0.6842 mL | 1.7105 mL | |
| 50 mM | 0.0547 mL | 0.2737 mL | 0.5474 mL | 1.3684 mL | |
| 60 mM | 0.0456 mL | 0.2281 mL | 0.4561 mL | 1.1404 mL | |
| 80 mM | 0.0342 mL | 0.1711 mL | 0.3421 mL | 0.8553 mL | |
| 100 mM | 0.0274 mL | 0.1368 mL | 0.2737 mL | 0.6842 mL |
(S)-NIK SMI1 Related Classifications
HY-112433A Related Classifications
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