Tigogenin (Standard)
Tigogenin (Standard) is a steroidal sapogenins. Tigogenin (Standard) can inhibit adipocytic differentiation and induce osteoblastic differentiation in mouse bone marrow stromal cells. Tigogenin (Standard) can inhibit cells proliferation and induce apoptosis. Tigogenin (Standard) can be used for the researches of cancer, inflammation, immunology, metabolic and cardiovascular disease, such as mammary gland carcinoma, rheumatoid arthritis, osteoporosis and atherosclerosis.
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- CAS No.: 77-60-1
- Formule: C27H44O3
- Masse moléculaire:416.64
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Product Information
Information
Application
The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.
Chemical Information
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CAS No. 77-60-1
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Masse moléculaire 416.64
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Formule C27H44O3
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SMILES
[H][C@]1(O[C@@]2(OC[C@H](C)CC2)[C@H]3C)C[C@@]4([H])[C@]5([H])CC[C@@]6([H])C[C@@H](O)CC[C@]6(C)[C@@]5([H])CC[C@]4(C)[C@]13[H]
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Structure Classification
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Initial Source
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
[1]. Zhou H, et al. Tigogenin inhibits adipocytic differentiation and induces osteoblastic differentiation in mouse bone marrow stromal cells. Mol Cell Endocrinol. 2007 May 30;270(1-2):17-22. [Content Brief]
[2]. Liagre B, et al. Inhibition of human rheumatoid arthritis synovial cell survival by hecogenin and Tigogenin (Standard) is associated with increased apoptosis, p38 mitogen-activated protein kinase activity and upregulation of cyclooxygenase-2. Int J Mol Med. 2007 Oct;20(4):451-60. [Content Brief]
[3]. Bao R, et al. Dioscin Ameliorates Hyperuricemia-Induced Atherosclerosis by Modulating of Cholesterol Metabolism through FXR-Signaling Pathway. Nutrients. 2022 May 9;14(9):1983. [Content Brief]
[4]. Michalak O, et al. Synthesis and anti-tumour, immunomodulating activity of diosgenin and Tigogenin (Standard) conjugates. J Steroid Biochem Mol Biol. 2020 Apr;198:105573. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)