TRPC3 agonist-1
TRPC3 agonist-1 (compound 4n) is a selective and competitive TRPC3 channel agonist. TRPC3 agonist-1 binds at L2 site of hTRPC3.
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- CAS No.: 1589567-51-0
- Formule: C22H23F3N4O3
- Masse moléculaire:448.44
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Activité biologique
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Chemical Information
- Pureté et documentation
- Références
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Help & FAQs
Activité biologique
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TRPC3 |
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Cell Line
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Type | Value | Description | References |
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| HEK293 | EC50 |
0.019 μM
Compound: 4n
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Agonist activity at human TRPC3 expressed in HEK293 cells assessed as induction of membrane depolarization measured for 2.5 mins in presence of 0.5 mM Ca2+ by FLIPR membrane potential dye-based fluorescence assay
Agonist activity at human TRPC3 expressed in HEK293 cells assessed as induction of membrane depolarization measured for 2.5 mins in presence of 0.5 mM Ca2+ by FLIPR membrane potential dye-based fluorescence assay
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[PMID: 28395140] |
Chemical Information
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CAS No. 1589567-51-0
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Masse moléculaire 448.44
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Formule C22H23F3N4O3
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SMILES
O=C(N1CCC(C2=NC3=C(C4=CC=C(C(F)(F)F)C=C4)C(C)=NN3C(O)=C2)CC1)OCC
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
TRPC3 agonist-1 Related Classifications
HY-179489 Related Classifications
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