WEE1-IN-11
WEE1-IN-11 (Compound 13) is a potent CDK2 inhibitor with an IC50 of 2.0 nM. WEE1-IN-11 inhibits NCI–H446, A427, OVCAR3, C33A,and WiDr cells with IC50s of 93.9, 34.5, 86.7, 23.1, and 85 nM, respectively.
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- CAS No.: 2975172-98-4
- Formule: C26H29FN8OS2
- Masse moléculaire:552.69
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Activité biologique
Description
Chemical Information
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CAS No. 2975172-98-4
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Masse moléculaire 552.69
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Formule C26H29FN8OS2
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SMILES
CN1CCN(C2=CC=C(NC3=NC=C(C4=CN=CS4)C(C5=CN=C(N6C[C@@H](F)CC6)S5)=N3)C=C2OC)CC1
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocole
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Cell Cytotoxicity Assay
Cytotoxicity assays are usually based on the assessment of cell membrane damage, which can also be indirectly detected by measuring cell viability. Detection methods include MTT assay, CKK-8 assay, LDH assay and ATP assay, etc.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)