2975172-98-4
2975172-98-4
Chemical Structure
WEE1-IN-11
- CAS No.: 2975172-98-4
- Formula:C26H29FN8OS2
- Molecular Weight:552.69
SMILES: CN1CCN(C2=CC=C(NC3=NC=C(C4=CN=CS4)C(C5=CN=C(N6C[C@@H](F)CC6)S5)=N3)C=C2OC)CC1
Biological Activity: WEE1-IN-11 (Compound 13) is a potent CDK2 inhibitor with an IC50 of 2.0 nM. WEE1-IN-11 inhibits NCI–H446, A427, OVCAR3, C33A,and WiDr cells with IC50s of 93.9, 34.5, 86.7, 23.1, and 85 nM, respectively[1].
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WEE1-IN-11 | WEE1-IN-11 (Compound 13) is a potent CDK2 inhibitor with an IC50 of 2.0 nM. WEE1-IN-11 inhibits NCI–H446, A427, OVCAR3, C33A,and WiDr cells with IC50s of 93.9, 34.5, 86.7, 23.1, and 85 nM, respectively. | |||||||||||||||||||||
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References
Keywords
