1069-31-4
Chemical Structure
DL-Ornithine hydrochloride
Synonym(s): DL-(±)-Ornithine hydrochloride
- CAS No.: 1069-31-4
- Formula:C5H13ClN2O2
- Molecular Weight:168.62
IUPAC Name: 2,5-diaminopentanoic acid hydrochloride
InChIKey: GGTYBZJRPHEQDG-UHFFFAOYSA-N
SMILES: NC(CCCN)C(O)=O.[H]Cl
Biological Activity: DL-Ornithine (DL-(±)-Ornithine) hydrochloride is an amino acid and also a urea cycle promoter. DL-Ornithine hydrochloride has the characteristics of low metabolic rate and rapid excretion, and only the L-enantiomer undergoes decarboxylation. In mice inoculated with L-1210 leukemia cells, DL-Ornithine hydrochloride is excreted in urine in its original form, and its conversion to carbon dioxide within 24 h is negligible. DL-Ornithine hydrochloride is mainly used in the urea cycle to eliminate excess nitrogen in the body and protect the kidneys[1][2].
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DL-Ornithine hydrochloride | 99.78% | DL-Ornithine (DL-(±)-Ornithine) hydrochloride is an amino acid and also a urea cycle promoter. DL-Ornithine hydrochloride has the characteristics of low metabolic rate and rapid excretion, and only the L-enantiomer undergoes decarboxylation. In mice inoculated with L-1210 leukemia cells, DL-Ornithine hydrochloride is excreted in urine in its original form, and its conversion to carbon dioxide within 24 h is negligible. DL-Ornithine hydrochloride is mainly used in the urea cycle to eliminate excess nitrogen in the body and protect the kidneys. | ||||||||||||||||||||
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- [1]. Hanpitakpong W, et al. High-performance liquid chromatographic method for determination of 2-difluoromethyl-DL-ornithine in plasma and cerebrospinal fluid. J Chromatogr B Analyt Technol Biomed Life Sci. 2003;788(2):221-231. [Content Brief]
- [2]. Weeks C E, et al. Inhibitors of polyamine biosynthesis V: In Vivo Effects of α‐methyl‐(±)‐ornithine and α‐methyl‐(±)‐ornithine tert‐butyl ester[J]. Journal of Pharmaceutical Sciences, 1977, 66(11): 1586-1589.
Keywords
