1177970-73-8
1177970-73-8
Chemical Structure
ERK Inhibitor II (Negative control)
- CAS. Nr.: 1177970-73-8
- Formula:C18H12N6O
- Molecular Weight:328.33
IUPAC Name: 5-(2-phenylpyrazolo[1,5-a]pyridin-3-yl)-1,2-dihydro-3H-pyrazolo[3,4-c]pyridazin-3-one
InChIKey: QMBDONCHHMIWFJ-UHFFFAOYSA-N
SMILES: O=C1NNC2=NN=C(C3=C4C=CC=CN4N=C3C5=CC=CC=C5)C=C21
Biological Activity: ERK Inhibitor II (Negative control) is an effective inhibitor of extracellular signal-regulated kinase (ERK). ERK Inhibitor II (Negative control) inhibits the activation of insulin receptor, which can be used in the study of diabetes[1][2].
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ERK Inhibitor II (Negative control) | ERK Inhibitor II (Negative control) is an effective inhibitor of extracellular signal-regulated kinase (ERK). ERK Inhibitor II (Negative control) inhibits the activation of insulin receptor, which can be used in the study of diabetes. | |||||||||||||||||||||
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References
- [1]. Rezania A, et al. Differentiation of human embryonic stem cells to the pancreatic endocrine lineage. World Intellectual Property Organization. WO2010051223.
- [2]. Anastassiadis T, et al. A highly selective dual insulin receptor (IR)/insulin-like growth factor 1 receptor (IGF-1R) inhibitor derived from an extracellular signal-regulated kinase (ERK) inhibitor. J Biol Chem. 2013 Sep 27;288(39):28068-77. [Content Brief]
