133012-00-7
133012-00-7
Chemical Structure
LTB4-IN-1
- CAS No.: 133012-00-7
- Formula:C26H30N2O4S
- Molecular Weight:466.59
IUPAC Name: 2-cycloheptyl-N-(methylsulfonyl)-2-(4-(quinolin-2-ylmethoxy)phenyl)acetamide
InChIKey: YAWBFCPZMALJCE-UHFFFAOYSA-N
SMILES: O=C(NS(=O)(C)=O)C(C1=CC=C(OCC2=NC3=CC=CC=C3C=C2)C=C1)C4CCCCCC4
Biological Activity: LTB4-IN-1 (Compound 6) is a leukotriene synthesis (LTB4) inhibitor with an IC50 of 70 nM[1].
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LTB4-IN-1 | LTB4-IN-1 (Compound 6) is a leukotriene synthesis (LTB4) inhibitor with an IC50 of 70 nM. | |||||||||||||||||||||
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References
- [1]. Hatzelmann A, et al. Inversely-correlated inhibition of human 5-lipoxygenase activity by BAY X1005 and other quinoline derivatives in intact cells and a cell-free system--implications for the function of 5-lipoxygenase activating protein. Biochem Pharmacol. 1994 Jun 15;47(12):2259-68. [Content Brief]
