152140-41-5
Chemical Structure
L-367773
- CAS No.: 152140-41-5
- Formula:C28H38N4O3S
- Molecular Weight:510.69
IUPAC Name: N-((1S,2S,4R)-1-(((2,3-dihydrospiro[indene-1,4'-piperidin]-1'-yl)sulfonyl)methyl)-7,7-dimethylbicyclo[2.2.1]heptan-2-yl)-2-(1H-imidazol-4-yl)acetamide
InChIKey: VQAVBHLGXVZOKM-RASJMTDNSA-N
SMILES: O=C(N[C@@H]1[C@](C2(C)C)(CS(=O)(N3CCC4(CC3)CCC5=C4C=CC=C5)=O)CC[C@]2([H])C1)CC6=CNC=N6
Biological Activity: L-367773 is an orally active, selective oxytocin receptor antagonist, with Ki values of 26 nM and 61 nM for rat uterine oxytocin receptor and human uterine oxytocin receptor, respectively. L-367773 inhibits Oxytocin-stimulated uterine contractions[1].
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L-367773 | L-367773 is an orally active, selective oxytocin receptor antagonist, with Ki values of 26 nM and 61 nM for rat uterine oxytocin receptor and human uterine oxytocin receptor, respectively. L-367773 inhibits Oxytocin-stimulated uterine contractions. | |||||||||||||||||||||
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Keywords
