1557138-61-0
1557138-61-0
Chemical Structure
UBA6-IN-1 hydrochloride
- CAS No.: 1557138-61-0
- Formula:C20H22ClN5O4S
- Molecular Weight:463.94
InChIKey: DIAPQBPRQUANEP-KFIVTFPCSA-N
SMILES: O[C@H]1C[C@H](N(C=C2)C3=C2C(C4=CC5=CC=CC=C5N4)=NC=N3)C[C@H]1COS(N)(=O)=O.Cl
Biological Activity: UBA6-IN-1 hydrochloride is a UBA6/UBE1L2 inhibitor (IC50 ≤50 nM) that acts by reducing the level of squalene epoxidase (SQLE). UBA6-IN-1 hydrochloride affects SREBP-dependent lipid metabolism processes and downstream cholesteryl ester transport, and can be used for cancer research[1].
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UBA6-IN-1 hydrochloride | UBA6-IN-1 hydrochloride is a UBA6/UBE1L2 inhibitor (IC50 ≤50 nM) that acts by reducing the level of squalene epoxidase (SQLE). UBA6-IN-1 hydrochloride affects SREBP-dependent lipid metabolism processes and downstream cholesteryl ester transport, and can be used for cancer research. | |||||||||||||||||||||
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