1622848-92-3
1622848-92-3
Chemical Structure
GSK2982772
- CAS No.: 1622848-92-3
- Formula:C20H19N5O3
- Molecular Weight:377.40
IUPAC Name: (S)-3-benzyl-N-(5-methyl-4-oxo-2,3,4,5-tetrahydrobenzo[b][1,4]oxazepin-3-yl)-1H-1,2,4-triazole-5-carboxamide
InChIKey: LYPAFUINURXJSG-AWEZNQCLSA-N
SMILES: O=C(C1=NC(CC2=CC=CC=C2)=NN1)N[C@H]3COC4=CC=CC=C4N(C)C3=O
Biological Activity: GSK2982772 is a potent, orally active and ATP competitive RIP1 kinase inhibitor with IC50 values of 16 nM and 20 nM for human and monkey RIP1, respectively[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
GSK2982772 | 99.79% | GSK2982772 is a potent, orally active and ATP competitive RIP1 kinase inhibitor with IC50 values of 16 nM and 20 nM for human and monkey RIP1, respectively. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
|
|
GSK2982772 (Standard) | ≥98% | GSK2982772 (Standard) is the analytical standard of GSK2982772 (HY-101760). This product is intended for research and analytical applications. GSK2982772 is a potent, orally active and ATP competitive RIP1 kinase inhibitor with IC50 values of 16 nM and 20 nM for human and monkey RIP1, respectively. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
Structural Analogs
-
Similarity Score 0.78
HY-161059ZB-R-55 -
Similarity Score 0.74
HY-156367RIPK1-IN-16 -
Similarity Score 0.71
HY-100131RGSK481 (Standard) -
Similarity Score 0.70
HY-148297Ocadusertib -
Similarity Score 0.68
HY-114371Eclitasertib -
Similarity Score 0.67
HY-157963RIPK1-IN-23 -
Similarity Score 0.60
HY-163390RIP1 kinase inhibitor 9 -
Similarity Score 0.56
HY-148253TP-030-1 -
Similarity Score 0.53
HY-111946GSK3145095 -
Explore the MedChemAI to find more analogs
