1623-93-4

4-Biphenylsulfonyl chloride Chemical Structure
1623-93-4

Chemical Structure

4-Biphenylsulfonyl chloride

  • CAS No.: 1623-93-4
  • Formula:C12H9ClO2S
  • Molecular Weight:252.72

IUPAC Name: [1,1'-biphenyl]-4-sulfonyl chloride

InChIKey: ALBQXDHCMLLQMB-UHFFFAOYSA-N

SMILES: ClS(C1=CC=C(C2=CC=CC=C2)C=C1)(=O)=O

Biological Activity: 4-Biphenylsulfonyl chloride is a synthetic intermediate that participates in the sulfonamide formation reaction to synthesize antiproliferative compounds. The derivatives of 4-Biphenylsulfonyl chloride inhibit human head and neck squamous cell carcinoma (HNSCC) cells by increasing PTEN expression and inhibiting the PI3K/Akt/mTOR pathway. 4-Biphenylsulfonyl chloride can be used in the development of anticancer drugs for HNSCC[1].

Cat. No. Product Name Purity Description Pricing
HY-W004121 		4-Biphenylsulfonyl chloride 99.59% 4-Biphenylsulfonyl chloride is a synthetic intermediate that participates in the sulfonamide formation reaction to synthesize antiproliferative compounds. The derivatives of 4-Biphenylsulfonyl chloride inhibit human head and neck squamous cell carcinoma (HNSCC) cells by increasing PTEN expression and inhibiting the PI3K/Akt/mTOR pathway. 4-Biphenylsulfonyl chloride can be used in the development of anticancer drugs for HNSCC.
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This compound is listed in the SVHC (Substances of Very High Concern) candidate list of ECHA (European Chemicals Agency).

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Structural Analogs

References

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