1639974-69-8
1639974-69-8
Chemical Structure
ATR-IN-1
- CAS No.: 1639974-69-8
- Formula:C18H19N7O
- Molecular Weight:349.40
IUPAC Name: (R)-3-methyl-4-(1-methyl-6-(1H-pyrrolo[2,3-d]pyridazin-4-yl)-1H-imidazo[4,5-c]pyridin-4-yl)morpholine
InChIKey: XCOKOJKTXOLUTM-LLVKDONJSA-N
SMILES: C[C@H]1N(C2=C3C(=CC(=N2)C4=C5C(NC=C5)=CN=N4)N(C)C=N3)CCOC1
Biological Activity: ATR-IN-1 is a selective ATR inhibitor with an IC50 of 0.5 nM. ATR-IN-1 inhibits the growth of ATM-deficient melanoma. ATR-IN-1 shows no hERG inhibitory effect. ATR-IN-1 can be used for research on melanoma[1].
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ATR-IN-1 | ATR-IN-1 is a selective ATR inhibitor with an IC50 of 0.5 nM. ATR-IN-1 inhibits the growth of ATM-deficient melanoma. ATR-IN-1 shows no hERG inhibitory effect. ATR-IN-1 can be used for research on melanoma. | |||||||||||||||||||||
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