167888-07-5
Chemical Structure
Olamufloxacin methanesulfonate
Synonym(s): HSR-903
- CAS No.: 167888-07-5
- Formula:C21H27FN4O6S
- Molecular Weight:482.53
InChIKey: QCRMQMNCFYYEFX-UTONKHPSSA-N
SMILES: CS(=O)(O)=O.N[C@H]1C2(CC2)CN(C(C(C)=C3N(C4CC4)C=C5C(O)=O)=C(F)C(N)=C3C5=O)C1
Biological Activity: Olamufloxacin (HSR-903) methanesulfonate is an orally active fluoroquinolone antibacterial agent. Olamufloxacin methanesulfonate inhibits DNA supercoiling activity. Olamufloxacin methanesulfonate exhibits activity against Gram-positive, Gram-negative, chlamydial, and quinolone-resistant bacterial strains. Olamufloxacin methanesulfonate can be used for the research of bacterial infections[1][2][3][4][5].
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Olamufloxacin methanesulfonate | Olamufloxacin (HSR-903) methanesulfonate is an orally active fluoroquinolone antibacterial agent. Olamufloxacin methanesulfonate inhibits DNA supercoiling activity. Olamufloxacin methanesulfonate exhibits activity against Gram-positive, Gram-negative, chlamydial, and quinolone-resistant bacterial strains. Olamufloxacin methanesulfonate can be used for the research of bacterial infections. | |||||||||||||||||||||
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- [1]. Yoshizumi S, et al. The in vivo activity of olamufloxacin (HSR-903) in systemic and urinary tract infections in mice. J Antimicrob Chemother. 2001;48(1):137-140. [Content Brief]
- [2]. Takahashi Y, et al. In vitro activity of HSR-903, a new quinolone. Antimicrob Agents Chemother. 1997;41(6):1326-1330. [Content Brief]
- [3]. Yoshizumi S, et al. In vivo activity of HSR-903, a new fluoroquinolone, against respiratory pathogens. Antimicrob Agents Chemother. 1998;42(4):785-788. [Content Brief]
- [4]. Niki Y, et al. In vitro and in vivo antichlamydial activities of HSR-903, a new fluoroquinolone antibiotic. Antimicrob Agents Chemother. 1997;41(4):857-859. [Content Brief]
- [5]. Deguchi T, et al. In-vitro antimicrobial activity of HSR-903, a new fluoroquinolone, against clinical isolates of Neisseria gonorrhoeae with quinolone resistance-associated alterations in GyrA and ParC. J Antimicrob Chemother. 1997;40(3):437-439. [Content Brief]
Keywords
