174513-95-2
Chemical Structure
Kalimantacin A
- CAS No.: 174513-95-2
- Formula:C30H48N2O7
- Molecular Weight:548.71
IUPAC Name: lithium 3-phenyl-1,2,4-oxadiazole-5-carboxylate
InChIKey: GENAAYFYLGYPIQ-FFPWVZAVSA-N
SMILES: O=C(O)/C=C(C)/CC(C)CC(CC/C=C/C=C/CC(C)CC(CC(O)CNC(C(C)C(OC(N)=O)C)=O)=O)=C
Biological Activity: Kalimantacin A is an Antibiotic. Kalimantacin A is produced by Alcaligenes sp. YL-02632S. Kalimantacin A inhibits bacterial fatty acid biosynthesis. Kalimantacin A exerts selective antibacterial activity against staphylococci, including multidrug-resistant Staphylococcus aureus and Staphylococcus epidermidis. Kalimantacin A shows no activity against most Gram-negative bacteria and fungi. Kalimantacin A exhibits anticancer activity against leukemia and cervical cancer. Kalimantacin A can be used in studies related to staphylococcal infections[1][2][3].
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Kalimantacin A | Kalimantacin A is an Antibiotic. Kalimantacin A is produced by Alcaligenes sp. YL-02632S. Kalimantacin A inhibits bacterial fatty acid biosynthesis. Kalimantacin A exerts selective antibacterial activity against staphylococci, including multidrug-resistant Staphylococcus aureus and Staphylococcus epidermidis. Kalimantacin A shows no activity against most Gram-negative bacteria and fungi. Kalimantacin A exhibits anticancer activity against leukemia and cervical cancer. Kalimantacin A can be used in studies related to staphylococcal infections. | |||||||||||||||||||||
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References
- [1]. Tokunaga T, et al. Kalimantacin A, B, and C, novel antibiotics produced by Alcaligenes sp. YL-02632S. II. Physico-chemical properties and structure elucidation. J Antibiot (Tokyo). 1996 Feb;49(2):140-4. [Content Brief]
- [2]. Thistlethwaite IRG, et al. Elucidation of the relative and absolute stereochemistry of the kalimantacin/batumin antibiotics. Chem Sci. 2017 Sep 1;8(9):6196-6201. [Content Brief]
- [3]. Kamigiri K, et al. Kalimantacins A, B and C, novel antibiotics from Alcaligenes sp. YL-02632S. I. Taxonomy, fermentation, isolation and biological properties. J Antibiot (Tokyo). 1996 Feb;49(2):136-9. [Content Brief]
