2040055-84-1
Chemical Structure
PF-4363467
- CAS No.: 2040055-84-1
- Formula:C22H30N2O3S
- Molecular Weight:402.55
IUPAC Name: (R)-N-(4-(4-ethylmorpholin-2-yl)-2-methylphenyl)-4-isopropylbenzenesulfonamide
InChIKey: SVIVAENOUMHBBT-QFIPXVFZSA-N
SMILES: CC1=C(NS(=O)(C2=CC=C(C=C2)C(C)C)=O)C=CC([C@@H]3CN(CCO3)CC)=C1
Biological Activity: PF-4363467, a dopamine D3/D2 receptor antagonist, attenuates opioid drug-seeking behavior without concomitant D2 side effects. PF-4363467 exhibits Ki values of 3.1 nM and 692 nM for D3R and D2R[1].
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PF-4363467 | PF-4363467, a dopamine D3/D2 receptor antagonist, attenuates opioid drug-seeking behavior without concomitant D2 side effects. PF-4363467 exhibits Ki values of 3.1 nM and 692 nM for D3R and D2R. | |||||||||||||||||||||
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Keywords