2095417-23-3
Chemical Structure
N2-(Isopropylphenoxyacetyl)-2’-O-propargylguanosine
- CAS No.: 2095417-23-3
- Formula:C24H27N5O7
- Molecular Weight:497.50
IUPAC Name: N-(9-((2R,3R,4R,5R)-4-hydroxy-5-(hydroxymethyl)-3-(prop-2-yn-1-yloxy)tetrahydrofuran-2-yl)-6-oxo-6,9-dihydro-3H-purin-2-yl)-2-(4-isopropylphenoxy)acetamide
InChIKey: HXWQCQDIIINIIH-UGTJMOTHSA-N
SMILES: OC[C@@H]1[C@@H](O)[C@@H](OCC#C)[C@H](N2C(NC(NC(COC3=CC=C(C(C)C)C=C3)=O)=NC4=O)=C4N=C2)O1
Biological Activity: N2-(Isopropylphenoxyacetyl)-2’-O-propargylguanosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1]. N2-(Isopropylphenoxyacetyl)-2’-O-propargylguanosine is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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N2-(Isopropylphenoxyacetyl)-2’-O-propargylguanosine | N2-(Isopropylphenoxyacetyl)-2’-O-propargylguanosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc. N2-(Isopropylphenoxyacetyl)-2’-O-propargylguanosine is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. | |||||||||||||||||||||
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