2361420-28-0
2361420-28-0
Chemical Structure
Cathepsin K-IN-9
- CAS No.: 2361420-28-0
- Formula:C35H41N7O
- Molecular Weight:575.75
InChIKey: WEQRHUDEDMRJFR-UHFFFAOYSA-N
SMILES: CNC1=NC(C#N)=NC2=C1C=C(N2CC(C)(C)C)C(NCC3=CC=C(C=C3)C4=CC=C(C=C4)C5CCN(CC5)C6CC6)=O
Biological Activity: Cathepsin K-IN-9 is a selective, potent and orally active Cathepsin K inhibitor with an IC50 of 6.2 nM. Cathepsin K-IN-9 has IC50 > 10000 nM for cathepsin B, L, and S, showing over 1600-fold selectivity. Cathepsin K-IN-9 has excellent safety and metabolic stability.Cathepsin K-IN-9 can be used for the research of osteoporosis[1].
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Cathepsin K-IN-9 | Cathepsin K-IN-9 is a selective, potent and orally active Cathepsin K inhibitor with an IC50 of 6.2 nM. Cathepsin K-IN-9 has IC50 > 10000 nM for cathepsin B, L, and S, showing over 1600-fold selectivity. Cathepsin K-IN-9 has excellent safety and metabolic stability.Cathepsin K-IN-9 can be used for the research of osteoporosis. | |||||||||||||||||||||
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References
Keywords
