2416234-31-4
2416234-31-4
Chemical Structure
Thalidomide-O-PEG1-OH
- CAS No.: 2416234-31-4
- Formula:C15H14N2O6
- Molecular Weight:318.28
InChIKey: HUGQAOWECNGJFB-UHFFFAOYSA-N
SMILES: O=C1NC(C(CC1)N2C(C3=C(C2=O)C(OCCO)=CC=C3)=O)=O
Biological Activity: Thalidomide-O-PEG1-OH is a PROTAC linker featuring thalidomide with an O-ethyl alcohol. Thalidomide is a ligand for E3 ligase, which ubiquitinylates proteins, thus committing their fate to proteolytic destruction. Meanwhile, the hydroxyl is a versatile handle for forming more complex structures through a number of reactions.
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Thalidomide-O-PEG1-OH | Thalidomide-O-PEG1-OH is a PROTAC linker featuring thalidomide with an O-ethyl alcohol. Thalidomide is a ligand for E3 ligase, which ubiquitinylates proteins, thus committing their fate to proteolytic destruction. Meanwhile, the hydroxyl is a versatile handle for forming more complex structures through a number of reactions. | |||||||||||||||||||||
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Keywords
