244094-72-2
244094-72-2
Chemical Structure
Betahistine-d3 dihydrochloride
- CAS No.: 244094-72-2
- Formula:C8H11D3Cl2N2
- Molecular Weight:212.13
IUPAC Name: N-(methyl-d3)-2-(pyridin-2-yl)ethan-1-amine dihydrochloride
InChIKey: XVDFMHARQUBJRE-GXXYEPOPSA-N
SMILES: [2H]C([2H])([2H])NCCC1=CC=CC=N1.Cl.Cl
Biological Activity: Betahistine-d3 (dihydrochloride) is the deuterium labeled Betahistine dihydrochloride. Betahistine dihydrochloride is an orally active histamine H1 receptor agonist and a H3 receptor antagonist[1]. Betahistine dihydrochloride is used for the study of rheumatoid arthritis (RA)[3].
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Betahistine-d3 dihydrochloride | 99.0% | Betahistine-d3 (dihydrochloride) is the deuterium labeled Betahistine dihydrochloride. Betahistine dihydrochloride is an orally active histamine H1 receptor agonist and a H3 receptor antagonist. Betahistine dihydrochloride is used for the study of rheumatoid arthritis (RA). | ||||||||||||||||||||
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Betahistine dihydrochloride (Standard) | ≥98% | Betahistine (dihydrochloride) (Standard) is the analytical standard of Betahistine (dihydrochloride). This product is intended for research and analytical applications. Betahistine dihydrochloride is an orally active histamine H1 receptor agonist and a H3 receptor antagonist. Betahistine dihydrochloride is used for the study of rheumatoid arthritis (RA). | ||||||||||||||||||||
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Betahistine-13C,d3 dihydrochloride | Betahistine-13C,d3 (dihydrochloride) is the 13C- and deuterium labeled Betahistine (dihydrochloride). Betahistine dihydrochloride is an orally active histamine H1 receptor agonist and a H3 receptor antagonist. Betahistine dihydrochloride is used for the study of rheumatoid arthritis (RA). | |||||||||||||||||||||
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Betahistine dihydrochloride | 99.82% | Betahistine dihydrochloride is an orally active histamine H1 receptor agonist and a H3 receptor antagonist. Betahistine dihydrochloride is used for the study of rheumatoid arthritis (RA). | ||||||||||||||||||||
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References
- [1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief]
- [3]. Gbahou F, et al. Effects of betahistine at histamine H3 receptors: mixed inverse agonism/agonism in vitro and partial inverse agonism in vivo.J Pharmacol Exp Ther. 2010 Sep 1;334(3):945-54. [Content Brief]
