247131-79-9
Chemical Structure
JTV-803 mesylate
- CAS No.: 247131-79-9
- Formula:C23H31N5O6S
- Molecular Weight:505.59
IUPAC Name: 4-(((2-carbamimidoyl-1,2,3,4-tetrahydroisoquinolin-7-yl)oxy)methyl)-1-(pyridin-4-yl)piperidine-4-carboxylic acid compound with methanesulfonic acid (1:1)
InChIKey: NOBZETMXGVAWIM-UHFFFAOYSA-N
SMILES: O=C(C1(CCN(CC1)C2=CC=NC=C2)COC3=CC=C4C(CN(CC4)C(N)=N)=C3)O.O=S(O)(C)=O
Biological Activity: JTV-803 mesylate is a human factor Xa inhibitor with oral anticoagulant activity. JTV-803 exhibits competitive inhibition of human factor Xa, with a Ki value of 0.019μM and IC50Value is 0.081μM. JTV-803 is 100 times more selective at inhibiting human factor Xa than its comparator. JTV-803 is an effective oral anticoagulant for the prevention of thrombosis[1].
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JTV-803 mesylate | JTV-803 mesylate is a human factor Xa inhibitor with oral anticoagulant activity. JTV-803 exhibits competitive inhibition of human factor Xa, with a Ki value of 0.019μM and IC50Value is 0.081μM. JTV-803 is 100 times more selective at inhibiting human factor Xa than its comparator. JTV-803 is an effective oral anticoagulant for the prevention of thrombosis. | |||||||||||||||||||||
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