256224-06-3
Chemical Structure
3’-O-MOE-G(iBu)-2’-phosphoramidite
- CAS No.: 256224-06-3
- Formula:C47H60N7O10P
- Molecular Weight:913.99
IUPAC Name: (2R,3R,4R,5R)-5-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-2-(2-isobutyramido-6-oxo-1,6-dihydro-9H-purin-9-yl)-4-(2-methoxyethoxy)tetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite
InChIKey: BWLKVJLYUDLOLH-SBCRAQIVSA-N
SMILES: COCCO[C@H]1[C@@H](OP(OCCC#N)N(C(C)C)C(C)C)[C@H](N2C(N=C(NC(C(C)C)=O)NC3=O)=C3N=C2)O[C@@H]1COC(C4=CC=CC=C4)(C5=CC=C(OC)C=C5)C6=CC=C(OC)C=C6
Biological Activity: 3’-O-MOE-G(iBu)-2’-phosphoramidite is a guanosine analog. Some guanosine analogs have immunostimulatory activity. In some animal models, they also induce type I interferons, producing antiviral effects. Studies have shown that the functional activity of guanosine analogs is dependent on the activation of Toll-like receptor 7 (TLR7)[1].
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3’-O-MOE-G(iBu)-2’-phosphoramidite | 3’-O-MOE-G(iBu)-2’-phosphoramidite is a guanosine analog. Some guanosine analogs have immunostimulatory activity. In some animal models, they also induce type I interferons, producing antiviral effects. Studies have shown that the functional activity of guanosine analogs is dependent on the activation of Toll-like receptor 7 (TLR7). | |||||||||||||||||||||
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Keywords
