2649837-82-9
2649837-82-9
Chemical Structure
HIV-1 inhibitor-19
- CAS No.: 2649837-82-9
- Formula:C24H22BClN2O5S
- Molecular Weight:496.77
IUPAC Name: (3-((5-chloro-3-((3,5-dimethylphenyl)sulfonyl)-1H-indole-2-carboxamido)methyl)phenyl)boronic acid
InChIKey: MYTFNSVNBUJDBU-UHFFFAOYSA-N
SMILES: O=C(C(N1)=C(S(=O)(C2=CC(C)=CC(C)=C2)=O)C3=C1C=CC(Cl)=C3)NCC4=CC(B(O)O)=CC=C4
Biological Activity: HIV-1 inhibitor-19 is a potent HIV-1 non-nucleoside reverse transcriptase inhibitor (NNRTI). HIV-1 inhibitor-19 maintains its inhibitory activity against L100I, K103N and V106A/ F227L mutant strains with EC50s of 7.3 nM, 9.2 nM and 21.0 nM, respectively[1].
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HIV-1 inhibitor-19 | HIV-1 inhibitor-19 is a potent HIV-1 non-nucleoside reverse transcriptase inhibitor (NNRTI). HIV-1 inhibitor-19 maintains its inhibitory activity against L100I, K103N and V106A/ F227L mutant strains with EC50s of 7.3 nM, 9.2 nM and 21.0 nM, respectively. | |||||||||||||||||||||
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Keywords
