2847066-15-1

Segigratinib hydrochloride Chemical Structure
2847066-15-1

Chemical Structure

Segigratinib hydrochloride

Synonym(s): 3D185; HH185

  • CAS No.: 2847066-15-1
  • Formula:C27H29Cl3N6O3
  • Molecular Weight:591.92

InChIKey: JJPRIOJLIKLSHO-UHFFFAOYSA-N

SMILES: O=C(C1=CC=C(N2CCNC(C)(C2)C)C=C1)NC3=NNC4=C3C=CC(C5=C(Cl)C(OC)=CC(OC)=C5Cl)=N4.Cl

Biological Activity: Segigratinib hydrochloride (3D185) is a potent inhibitor of FGFR1/2/3 and CSF-1R; The IC50 values for FGFR1, FGFR2, FGFR3 and CSF-1R are 0.5, 1.3, 3.6 and 3.8 nM, respectively. Segigratinib hydrochloride has antitumor activity[1].

Cat. No. Product Name Purity Description Pricing
HY-159503A 		Segigratinib hydrochloride Segigratinib hydrochloride (3D185) is a potent inhibitor of FGFR1/2/3 and CSF-1R; The IC50 values for FGFR1, FGFR2, FGFR3 and CSF-1R are 0.5, 1.3, 3.6 and 3.8 nM, respectively. Segigratinib hydrochloride has antitumor activity.
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