29706-84-1
29706-84-1
Chemical Structure
3′-Azido-3′-deoxy-5′-O-(triphenylmethyl)thymidine
- CAS No.: 29706-84-1
- Formula:C29H27N5O4
- Molecular Weight:509.56
IUPAC Name: 1-((2R,4S,5S)-4-azido-5-((trityloxy)methyl)tetrahydrofuran-2-yl)-5-methylpyrimidine-2,4(1H,3H)-dione
InChIKey: AZPSSDWPMSICSH-JIMJEQGWSA-N
SMILES: O=C(C(C)=C1)NC(N1[C@@H]2O[C@H](COC(C3=CC=CC=C3)(C4=CC=CC=C4)C5=CC=CC=C5)[C@@H](N=[N+]=[N-])C2)=O
Biological Activity: 3′-Azido-3′-deoxy-5′-O-(triphenylmethyl)thymidine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
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3′-Azido-3′-deoxy-5′-O-(triphenylmethyl)thymidine | 3′-Azido-3′-deoxy-5′-O-(triphenylmethyl)thymidine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc. | |||||||||||||||||||||
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